Essential Equipment for Biopharmaceutical Laboratories
A comprehensive guide to the critical instruments needed for drug discovery, protein analysis, and biopharmaceutical production.
Cell Culture Systems

Class II Biological Safety Cabinet
Provides a sterile work environment for cell culture procedures while protecting both the operator and the environment. Essential for handling mammalian cell lines and primary cultures.

CO₂ Incubator
Maintains optimal conditions (37°C, 5% CO₂, and controlled humidity) for mammalian cell growth. Modern models include HEPA filtration and copper-lined chambers to prevent contamination.
Protein Purification Equipment

AKTA Pure Chromatography System
Automated FPLC system for protein purification using various chromatography techniques including affinity, ion exchange, and size exclusion. Features UV, pH, and conductivity monitoring.

Tangential Flow Filtration System
Used for concentration and buffer exchange of protein solutions. Available with various molecular weight cut-off membranes to accommodate different biomolecules.
Analytical Instruments

UHPLC/HPLC System
High-performance liquid chromatography system for analyzing protein purity and stability. Equipped with photodiode array and fluorescence detectors for comprehensive analysis.

LC-MS Mass Spectrometer
Liquid chromatography-mass spectrometry system for protein identification, characterization, and post-translational modification analysis. Essential for biopharmaceutical quality control.
Molecular Biology Tools

Real-Time PCR System
Quantitative PCR instrument for analyzing gene expression levels and vector copy numbers in recombinant cell lines. Features multiplexing capability for high-throughput analysis.

Gel Electrophoresis Systems
Complete systems for DNA, RNA, and protein electrophoresis analysis. Includes power supplies, gel documentation systems, and analysis software for accurate molecular weight determination.
Quality Control Equipment

Multimode Microplate Reader
Measures absorbance, fluorescence, and luminescence for various assays including ELISA, protein quantification, and cell viability tests. Essential for high-throughput screening.

Dynamic Light Scattering Instrument
Analyzes protein size distribution and aggregation state with high sensitivity. Requires minimal sample volume and provides rapid results for formulation development.